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目的:通过观察以高压氧(HBO)为主的综合治疗对持续性植物状态(PVS)的疗效探讨HBO的作用机理。方法:对以用HBO为主综合治疗的PVS168例(HBO组)和以一般药物等治疗的PVS86例(非HBO对照组)的疗效进行比较,同时分析其中对HBO治疗效果有明显影响的几个因素。结果:HBO组的总有效率为83.3%,非HBO对照组的总有效率为54.6%;两者相比有非常显著性差异(P<0.01),HBO组的疗效明显为优。结论:HBO对PVS有显著的治疗作用,且其疗效与患者的年龄、HBO治疗的次数、PVS的原因和发生PVS后至开始进行HBO治疗的时间早晚有关。
OBJECTIVE: To investigate the mechanism of HBO by observing the efficacy of HBO-based combination therapy on persistent vegetative state (PVS). Methods: The efficacy of HBO-based combination PVS168 (HBO group) and PVS86 (non-HBO control group) treated with general drugs were compared, and the effect of HBO on the therapeutic effect of HBO factor. Results: The total effective rate of HBO group was 83.3%, while that of non-HBO control group was 54.6%. There was a significant difference between the two groups (P <0.01). The curative effect of HBO group was obvious Excellent. Conclusions: HBO has a significant therapeutic effect on PVS, and its efficacy is related to the patient’s age, the number of HBO treatments, the causes of PVS and the time from the onset of PVS to the start of HBO treatment.