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通过经面罩无创性和经鼻气管内插管有创性两种持续正压通气方式，对３１例慢性阻塞性肺疾病并严重呼吸衰竭、意识障碍的患者进行了对照性研究分析。发现在治疗后气插管组ＰａＯ２、ＰａＣＯ２、意识障碍和呼吸肌疲劳征象的改善均优于面罩组。而面罩组在剔除治疗无效的８例患者后，其余７例的疗效与插管组相似。结论认为对有意识障碍的严重呼吸衰竭患者应有选择性地使用面罩通气方式，治疗效果良好，并可减少对有创性气管插管机械通气的需求及并发症。
Thirty-two patients with chronic obstructive pulmonary disease and severe respiratory failure and unconsciousness were compared and studied by noninvasive mask and invasive nasal endotracheal intubation. It was found that the improvement of PaO2, PaCO2, disturbance of consciousness and respiratory muscle fatigue in the intubation group was better than that in the mask group after treatment. The mask group in the exclusion of treatment ineffective in 8 patients, the remaining seven cases of efficacy and intubation group similar. Conclusions: Mask ventilation should be used selectively in patients with severe respiratory failure who have impaired consciousness. The treatment effect is good and the demand and complications of invasive endotracheal mechanical ventilation can be reduced.