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急性心肌梗死患者心肌梗死面积及左室功能的变化对患者的临床治疗效果及判断预后有着十分重要的意义。曲美他嗪是目前抗心肌缺血代谢疗法的一种重要药物。它抑制脂肪酸氧化和刺激葡萄糖氧化,并对缺血的心肌细胞提供一定程度的保护作用,而且不影响血流动力学。临床应用日益广泛,本文就曲美他嗪与急性心肌梗死的研究进展予以综述。
The changes of myocardial infarction area and left ventricular function in acute myocardial infarction patients are of great significance for the clinical treatment and prognosis of patients. Trimetazidine is currently an important anti-myocardial ischemic drug therapy. It inhibits fatty acid oxidation and stimulates glucose oxidation, and provides some protection to ischemic cardiomyocytes without affecting hemodynamics. The clinical application is more and more widely. This article reviews the research progress of trimetazidine and acute myocardial infarction.