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近两年来应用尼群地平、依那普利联合治疗老年原发性高血压38例,报告如下。 1 对象与方法 1.1 对象:随机选择新入院老年性高血压患者38例,男性30例,女性8例。平均年龄65.4±6.4岁,为联合用药组,诊断及分期按WHO标准,Ⅰ期6例,Ⅱ期22例,Ⅲ期10例。病程3~26年不等。合并冠心病16例,慢性阻塞性肺疾病10例,糖尿病2例。另选住院老年高血压患者34例;男性28例,女性6例。平均年龄66.2±5.8岁,为单用尼群地平对照组,其分期、病程及并发症与联合用药组相似。 1.2 方法:两组治疗前停服各种降压药2周。联合治疗组用尼群地平10mg,PO,Bid;依那普利5mg~10mg,PO,Bid。单用尼群地平对照组服用尼群地平
The past two years, the application of nitrendipine, enalaprol combined treatment of 38 cases of elderly essential hypertension, the report is as follows. 1 Subjects and Methods 1.1 Subjects: Randomly selected 38 new cases of hospitalized elderly patients with hypertension, 30 males and 8 females. The mean age was 65.4 ± 6.4 years old. For the combination group, the diagnosis and staging were based on WHO criteria. There were 6 cases in stage Ⅰ, 22 cases in stage Ⅱ and 10 cases in stage Ⅲ. Duration of 3 to 26 years. 16 cases of coronary heart disease, chronic obstructive pulmonary disease in 10 cases, 2 cases of diabetes. Another 34 elderly patients with hypertension were hospitalized; 28 males and 6 females. The mean age was 66.2 ± 5.8 years. The control group was nitrendipine alone. The staging, course of disease and complications were similar to the combination group. 1.2 Methods: two groups before stopping taking a variety of antihypertensive drugs for 2 weeks. Combination therapy group with nitrendipine 10mg, PO, Bid; Enalapril 5mg ~ 10mg, PO, Bid. Nitrendipine alone in the control group took nitrendipine