正常儿童三种空间频率多导视觉诱发电位地形图的研究

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目的探讨正常儿童三种空间频率多导视觉诱发电位地形图的变化特征。方法选取13.7,27.5及55三种方格进行正常儿童88眼多导视觉诱发电位地形图的研究。结果(1)正常儿童三种空间频率的P1潜伏期及N1P1振幅在O1,Oz和O2导有显著差异,13.7方格P1潜伏期明显延迟于27.5及55方格,而N1P1振幅显著低于后两者。(2)在三种空间频率,P1潜伏期及N1P1振幅在中线两侧对应导联分布对称,在侧连线位,N1P1振幅于O1/O2,T5/T6与Oz导联之间有显著差别,以Oz导联振幅最大,T5/T6导联振幅最低;P1潜伏期在Oz位最短,向T5/T6位明显延迟,两者有统计学差异。在中线前后导联,也是以Oz导P1潜伏期最短,N1P1振幅最大,由Oz向Cz则潜时逐渐延迟,波幅下降。(3)地形图特征:88眼中有71眼地形图呈对称分布,17眼枕区高电位活动偏向一侧枕区,以向左侧枕区偏移为主。结论多导视觉诱发电位的P1潜伏期及N1P1振幅受空间频率的影响;随着空间频率的增大,P1潜伏期逐渐缩短,N1P1振幅逐渐增大。P1潜伏期及N1P1振幅在中线两侧对称分布,但地形图则有部分儿童呈现不对称分布,表明部分儿童两侧大? Objective To investigate the changes of topography of three kinds of space-frequency multi-channel visual evoked potentials in normal children. Methods The three tracts of 13.7, 27.5 and 55 were selected to study the 88 eyes of multifocal visual evoked potentials in normal children. Results (1) P1 latency and N1P1 amplitude of three spatial frequencies in normal children were significantly different between O1, Oz and O2. The latency of 13.7  squares P1 was obviously delayed by 27.5  and 55  squares, while N1P1 Amplitude was significantly lower than the latter two. (2) At the three spatial frequencies, P1 latency and N1P1 amplitude were symmetrical in the corresponding leads on both sides of the midline. There was a significant difference in N1P1 amplitude between O1 / O2 and T5 / T6 and Oz leads at the sidelines, The amplitude of the lead of Oz was the largest and the amplitude of the lead of T5 / T6 was the lowest. The latency of P1 was the shortest at Oz and significantly delayed at T5 / T6, both of which had statistical difference. In the midline before and after the lead, but also to Oz lead P1 shortest incubation period, N1P1 maximum amplitude, from Oz to Cz is the potential delay of the delay, amplitude decreased. (3) topographic features: There are 71 eyes of 88 eyes were symmetrical distribution, 17 occipital high potential activity side of the pillow to the left, mainly to the left occipital offset. Conclusion P1 latency and N1P1 amplitude of multi-conduction visual evoked potential are affected by spatial frequency. As space frequency increases, P1 latency gradually decreases and N1 P1 amplitude gradually increases. P1 latency and N1P1 amplitude were symmetrically distributed on both sides of the midline, but some children in the topographic map showed an asymmetrical distribution, indicating that some children were large on both sides of the midline.
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