药物致畸

来源 :中国药房 | 被引量 : 0次 | 上传用户:xinyang101
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
妊娠期用药直接关系到下一代的发育成长和身体健康。60年代初孕妇服用“反应停”引起震惊世界的畸胎事件后,各国对药物的致畸作用非常关注。就我国目前情况而言,随着新药的大量涌现,由于一些地区,特别是基层单位和广大农村缺乏胚胎药理学知识,滥用药物引起畸胎的现象时有发生,这对我国的计划生育、优生优育的基本国策、提高人口素质无疑是一个至关重要的问题。为此,本文仅就一些常用药物的致畸作用作一简介。 Pregnancy medication is directly related to the development and health of the next generation. Early 60s pregnant women take “reaction stop” caused by the teratogenic events that shocked the world, the teratogenic effects of various countries are very concerned about the drug. As far as the current situation in our country is concerned, with the massive emergence of new drugs, the phenomenon of teratogenicity caused by drug abuse has occurred from time to time in some areas, especially grass-roots units and the vast rural areas, lack of knowledge of embryo pharmacology. This has caused great impacts on family planning, The basic national policy of good education and improving the quality of the population are undoubtedly a crucial issue. To this end, this article only on the teratogenicity of some commonly used drugs for a brief introduction.
其他文献
目的:观察加味四物汤对自发性高血压大鼠(SHR)的心肌组织基因表达谱的影响。方法:提取实验组和对照组SHR心肌组织RNA,用Cy-5,Cy-3逆转录荧光标记制作cDNA探针与表达谱基因芯
医院感染病例上报的及时性和正确性,在预防与控制医院感染中有着重要意义,已成为医院感染管理工作中不可缺少的一个环节。在工作实践中,对本院存在的问题进行分析,并采取相应
Aim: To assess the spatial and temporal expression of germ cell nuclear factor (GCNF) in male mouse germ cells during postnatal development and in sperm before
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
赵大鸣谈晚会创作体会,可用两句话概括其要:深刻理解主题内容;充分运用艺术规律。时代在发展,“长征”作为中国革命史和现代中国社会历史发展的重大课题,史实研究和理论认识
观察饮食性肥胖(Dietary Induced Obesity,DIO)大鼠、饮食性肥胖抵抗型(DietaryInduced Obesity Resistance,DIO-R)大鼠及对照组大鼠糖耐量和血浆胰岛素的变化,DIO大鼠给予30
甲基黄酮醇胺(MPA)40mg·Kg~(-1)iv,能使花生四烯酸(AA)诱发的小鼠死亡率降低61%.MFA12.5~200μmol·L~(-1)呈剂量依赖性地抑制AA诱导的免血小板聚集.聚集率为49%±10%~4%±4%,对照
目的:探讨大力新合剂对小鼠耐缺氧及抗疲劳作用。方法:取小鼠随机分成4组,对照组、大力新合剂高、中、低(2.30,1.15,0.575g.kg-1)剂量组。采用常压耐缺氧法记录小鼠缺氧存活
今天,药品市场销售已成为最有生气的和变化最大的领域之一。不断的变化已成为正常现象。在不久以前,药品的销售方式还是非常简单的,销售的对象就是医生。销售的途径大部分是
A neutral metalloprotease was purified from the cultured mycelia of Laccocephalum mylittae,an effective medicinal fungus widely used in anthelmintic therapy.The