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目的探讨影响结肠癌转移的危险因素。方法采用Cox回归分析法对2005年1月-2008年12月结肠癌转移的各种影响因素进行单因素筛选,单因素筛选后有意义的指标进行多因素分析。结果肝脏转移发生率最高,淋巴结转移、辅助化疗、分化程度及术后癌胚抗原水平4项指标与结肠癌的转移有关,均为危险因素。结论肝脏转移发生率最高。4项影响转移的危险因素中,淋巴结转移的危险性最大,可以视作影响手术后预后的重要因素。
Objective To explore the risk factors that affect the metastasis of colon cancer. Methods Cox regression analysis was used to analyze the various influencing factors of colon cancer metastasis from January 2005 to December 2008 by single factor screening and multivariate analysis after meaningful selection by single factor screening. Results The highest incidence of liver metastasis, lymph node metastasis, adjuvant chemotherapy, differentiation and postoperative carcinoembryonic antigen level 4 indicators and metastasis of colon cancer, are risk factors. Conclusion The highest incidence of liver metastases. Of the four risk factors affecting metastasis, the risk of lymph node metastasis is the greatest, which can be regarded as an important factor affecting postoperative prognosis.