随着高效抗生素的广泛应用和免疫损伤患者增加,播散性念珠菌病已成为普遍的医疗问题。两性霉素 B 为治疗念珠菌病的常用药物,但它毒性大,疗效不明确。Echinoca-ndinB 的唯一同类药 Cilofungin,通过抑制细胞壁的合成而杀灭念珠菌。在动物实验中它能有效地治疗念珠菌病,故人们寄希望于 With the widespread use of high-potency antibiotics and the increasing number of immunocompromised patients, disseminated candidiasis has become a widespread medical problem. Amphotericin B for the treatment of candidiasis commonly used drugs, but it is toxic, curative effect is not clear. Cilofungin, the only congener of Echinoca-ndinB, kills Candida by inhibiting cell wall synthesis. In animal experiments it can effectively treat candidiasis, so people hope