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目的:观察药品不良反应(ADR)发生情况,探讨药品不良反应发生因素,总结药品不良反应发生规律,促进合理用药。方法:选取349例药品不良反应报告作为研究对象,从患者年龄、性别、药品种类、给药途径、器官损害表现及程度等方面进行统计分析。结果:经调查分析,年龄较大人群有170例(48.71%),静脉注射、口服给药引起的ADR分别有161例(46.13%)、177例(50.72%),中药制剂类不良反应发生率为32.95%。结论:增强合理用药意识,完善防范处理方案,指导患者合理服用药物,同时加强ADR监测,保障用药安全。
Objective: To observe the occurrence of adverse drug reactions (ADR), to explore the adverse drug reaction factors, summarize the occurrence of adverse drug reactions, and promote the rational use of drugs. Methods: A total of 349 cases of adverse drug reactions were selected as research objects, and the statistical analysis was made on the aspects of patient’s age, gender, drug type, route of administration, organ damage performance and degree. Results: After investigation, 170 cases (48.71%) were found in the older population. ADR caused by intravenous injection and oral administration were 161 (46.13%) and 177 (50.72%) respectively. The incidence of adverse drug reactions Is 32.95%. Conclusion: To enhance the awareness of rational drug use, improve the precautionary treatment programs, guide patients to take drugs reasonably, and strengthen the monitoring of ADR to ensure drug safety.