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53±11(37～71)岁的53(男40、女13)例慢性稳定型心绞痛患者经造影证实存在冠脉病变。在停用抗心绞痛药物至少48小时后进行试验。所有53例在冠脉内注入1mg硝异山梨醇前、后分别作冠脉造影。其中21例首先在冠脉内缓慢注入(1min)20～30μg麦角新碱,并在注药后5min、10min作冠脉造影(作为对照),然后再在冠脉内注入1mg硝异山梨醇,隔2～4min再作冠脉造影。
Coronary lesions were confirmed by radiography in 53 ± 11 (37-71) -year-old 53 (40 male and 13 female) patients with chronic stable angina. The trial was stopped after the anti-anginal medication was stopped for at least 48 hours. All 53 cases were injected with 1 mg of isosorbide before and after coronary angiography. 21 of them were firstly injected with 20 ~ 30μg ergometrine slowly (1min) into the coronary artery and coronary angiography (control) 5min and 10min after injection, and then 1mg of isosorbide mononitrate was injected into the coronary artery, Every other 2 ~ 4min coronary angiography.