论文部分内容阅读
：采用器官培养法培养新生小鼠的颅盖骨，在３种细胞因子作用４８ｈ后，用原子吸收光谱仪测定上清液内钙含量。结果：３种细胞因子在实验浓度范围内均能促进上清液中钙含量增加，并且具有一定的剂量依赖特点。结论：肿瘤坏死因子、白细胞介素－１、白细胞介素－６能够刺激新生小鼠颅盖骨的骨吸收，是与骨吸收密切相关的细胞因子。
The calvaria of neonatal mice were cultured by organ culture method. After three kinds of cytokines were treated for 48 hours, the content of calcium in supernatant was measured by atomic absorption spectrometry. Results: All the three cytokines promoted the increase of calcium in the supernatant within the experimental concentration range, and had certain dose-dependent characteristics. CONCLUSION: Tumor necrosis factor, interleukin-1 and interleukin-6 can stimulate bone resorption in neonatal mouse calvaria and are closely related to bone resorption.