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近年来,缺血性心、脑血管疾病的血流动力学改变已受到临床重视,许多学者认为血流动力学变化是心、脑血管疾病的危险因素.我院自1993年4月以来,用精制蝮蛇抗栓酶-3(Srate-3)治疗缺血性心、脑血管疾病112例,现将治疗前后血流动力学及血脂各项指标的改变进行分析.1 资料和方法1.1 一般资料 112例按心脏病、脑血管病诊断标准确诊的缺血性心、脑血管疾病,男58例,女54例.年龄36～84岁,平均年龄58.7岁.脑血管病人52例,心血管病人60例.1.2 治疗方法 应用Srate-3皮试阴性后,先用生理盐水20ml加Svate-31.0单位静注,后用生理盐水250ml加Svate-3 1.0单位静滴,均每日1次.静脉注射7天后停止,静滴连续21天为1个疗程,一般根据病情治疗1～3个疗程
In recent years, hemodynamic changes of ischemic heart and cerebrovascular disease have received clinical attention, many scholars believe that hemodynamic changes are risk factors of heart and cerebrovascular disease.Our hospital since April 1993 with Purified viper antithrombin-3 (Srate-3) treatment of ischemic heart and cerebrovascular disease in 112 cases, now before and after treatment hemodynamics and blood lipid indicators were analyzed.1 Data and methods 1.1 General Information 112 cases were diagnosed as ischemic heart and cerebrovascular disease according to diagnostic criteria of heart disease and cerebrovascular disease, including 58 males and 54 females, aged from 36 to 84 years with a mean age of 58.7 years, 52 cases of cerebrovascular disease, 60 cases .1.2 treatment method Srate-3 skin test negative, first with saline 20ml Svate-31.0 units intravenous injection of normal saline 250ml plus Svate-3 1.0 units intravenously once a day. 7 days after the stop, intravenous infusion of 21 consecutive days for a course of treatment, the general treatment of the disease according to 1 to 3 courses