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目的:探讨血清β-人绒毛膜促性腺激素(β-HCG)、孕酮动态监测在异位妊娠早期诊断中的应用。方法:应用电化学发光法检测异位妊娠和正常宫内妊娠妇女血清β-HCG和孕酮水平,比较2组妊娠血清β-HCG和孕酮水平变化。结果:观察组第4周β-HCG水平与对照组比较差异无统计学意义(P>0.05),孕酮水平显著低于对照组(P<0.05),第5、6周血清孕酮和β-HCG水平均显著低于对照组(P<0.05)。结论:血清孕酮和β-HCG动态监测可早期诊断异位妊娠,可减少误诊和漏诊,并对治疗方案的选择和预后判断具有重要的指导作用。
Objective: To investigate the application of serum β-human chorionic gonadotropin (β-HCG) and progesterone in early diagnosis of ectopic pregnancy. Methods: The levels of serum β-HCG and progesterone in ectopic and normal uterine pregnant women were detected by electrochemiluminescence. The level of β-HCG and progesterone in pregnant women were compared. Results: There was no significant difference in β-HCG level between the observation group and the control group in the 4th week (P> 0.05), and the level of progesterone in the observation group was significantly lower than that of the control group (P <0.05) -HCG levels were significantly lower than the control group (P <0.05). Conclusion: Serum progesterone and β-HCG can early diagnose ectopic pregnancy, which can reduce the misdiagnosis and missed diagnosis. It also plays an important guiding role in the selection and prognosis of treatment.