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不育与癌变一直是治疗的重点和难点。近年来,对隐睾(cryptorchidism)不育和癌变的研究已从组织学和激素学发展到细胞学,即生殖母细胞迁移障碍或延迟可能是隐睾不育与癌变的关键因素;支持细胞及间质细胞发育缺陷直接或间接导致生殖母细胞迁移障碍或延迟。≤4岁行睾丸固定术的隐睾患者预后较好,且近年的趋势主张早期治疗性干预,手术治疗可于出生数月进行,然而对1～3岁患儿行激素治疗,可能会抑制精原细胞的增长。抑制素B和FSH可作为隐睾患者生育潜能的预测指标之一。
Infertility and canceration have always been the focus and difficulty of treatment. In recent years, studies on cryptorchidism infertility and canceration have progressed from histology and hormoneology to cytology, that is, the impediment or delay of germ cell migration may be the key factor of cryptorchidism infertility and canceration; the supportive cells and Defective stromal cells directly or indirectly lead to impaired or delayed gonadal migration. Patients with cryptorchidism who underwent testicular fixation less than 4 years old had a good prognosis, and in recent years the trend advocated early therapeutic intervention. Surgical treatment can be performed at several months of birth. However, hormone therapy in children aged 1-3 years may inhibit the development of cryptorchidism. Proto-cell growth. Inhibin B and FSH can be used as predictors of fertility in cryptorchidism patients.