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【目的】通过对188例高危儿的早期干预效果对比分析,总结高危早期干预的最佳方式。【方法】将2006年1月-2008年12月宜都市妇幼保健院首次就诊筛查出的408例高危儿为研究对象。按自愿原则将其中的188例作为干预组,进行动作、认知、语言、视听及物理作业、药物治疗等综合干预,医院干预与家庭干预相结合;其余220例作为未干预组,只进行家庭运动训练、抚触及视听等。同期160例正常儿童作为对照组。3组儿童在出生后6、9、12、18月时测量身长、体重、头围等体格发育指标,同时进行婴幼儿智能发育测试。【结果】干预组与未干预组比较,除6月时的体重、头围及9月时的体重差异无统计学意义(P>0.05)外,其余月龄的体格发育指标及智能发育水平干预组优于未干预组,差异均有统计学意义(P<0.05);未干预组与对照组比较,除6月时体重、头围外,其余体格发育指标差异有统计学意义(P<0.05),智能发育水平差异有高度统计学意义(P<0.01);而对照组与干预组在体格发育及智能发育方面差异无统计学意义(P>0.05)。干预组儿童预后优于未干预组,差异有统计学意义(P<0.05)。【结论】高危儿早期干预可明显提高其生存质量。
【Objective】 By analyzing the effect of early intervention in 188 high-risk infants, the best way of high-risk early intervention is summarized. 【Methods】 A total of 408 high-risk infants screened from the first visit of Yidu MCH in January 2006-December 2008 were selected as research subjects. According to the principle of voluntariness, 188 cases were taken as the intervention group, and combined intervention such as movement, cognition, language, audiovisual and physical work, drug treatment and so on, the hospital intervention combined with family intervention; the other 220 cases were treated as the intervention group Exercise training, touch and audio-visual and so on. 160 normal children in the same period served as the control group. The 3 groups of children measured physical growth indexes such as body length, body weight and head circumference at 6, 9, 12, and 18 months after birth, and tested the intelligence development of infants and young children at the same time. 【Results】 Compared with the non-intervention group, body weight, head circumference and body weight at 6 months were no significant difference (P> 0.05), other physical development indicators and level of intelligence development intervention (P <0.05). Compared with the control group, there was significant difference in the physical development indexes except the body weight and head circumference in June (P <0.05), and the difference was statistically significant ), There was a significant difference in the level of intelligence development (P <0.01). There was no significant difference between the control group and the intervention group in physical development and intelligence development (P> 0.05). The prognosis of intervention group was better than that of non-intervention group, the difference was statistically significant (P <0.05). 【Conclusion】 Early intervention with high-risk children can significantly improve their quality of life.