我们于1963年对加大组胺胃液分泌试验作了临床研究,认为该法比较准确、重复性较好、可对壁细胞作出数量估计,有助于分析胃酸分泌的病理生理功能。近年来,国内外学者巳应用五肽胃泌素测定胃酸分泌功能,其效果与加大组胺试验雷同,而副作用较小。国内尚缺少两种试验相互对比的临床资料。我们进行了对比试验,现报道如下。 In 1963, we conducted a clinical study on increasing the secretion of histamine in gastric juice. We believe that this method is more accurate, reproducible, estimates the number of parietal cells, and is helpful to analyze the pathophysiological function of gastric acid secretion. In recent years, domestic and foreign scholars have applied pentagastrin to determine gastric acid secretion, the effect of which is similar to that of increasing histamine test, with less side effects. There is still lack of clinical data comparing the two trials in China. We conducted a comparative test and are reported below.