患者 ,女 ,48岁 ,汉族 ,石家庄市人。因腹胀、纳差、尿黄伴乏力 2 0ｄ入院。患者于入院前使用利福平、异菸肼抗痨治疗 ,服药过程中出现腹胀、进食减少、尿色加深 ,如浓茶水色 ;肝功能 :谷丙转氨酶 5 3 8Ｕ/Ｌ ,总胆红素 72 .1μｍｏｌ/Ｌ ,遂来我院住院。查体 :皮肤、巩膜明显 Patient, female, 48 years old, Han nationality, Shijiazhuang city. Due to abdominal distension, anorexia, urine yellow with fatigue 20d admission. Patients in the hospital before the use of rifampicin, isoniazid anti-tuberculosis treatment, medication during bloating, eating less, darker urine, such as concentrated tea color; liver function: alanine aminotransferase 538U / L, total bilirubin 72.1μmol / L, then came to our hospital. Physical examination: skin, sclera obvious