2009-2011年新疆手足口病流行病学及病原学特征分析

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目的分析2009-2011年新疆手足口病流行特征及病原谱变化规律,为控制手足口病疫情提供科学依据。方法从中国疾病预防控制信息系统中将新疆2009-01-01/2011-12-31的手足口病报告病例网络直报信息导出,并用描述性流行病学方法对手足口病报告病例资料进行分析。结果 2009-2011年新疆手足口病3年的总发病数18 184例,其中实验室诊断病例1 648例,占总数的8.95%;总发病率为28.10/10万。3年来在全疆手足口病报告病例中,乌鲁木齐市(5596例)持续居第1位;而实验室诊断病例中居第1位的同样也是乌鲁木齐市(629例)。报告病例主要集中在0~5岁年龄段(16 236例),占发病总数的89.29%,男性高于女性;以散居儿童和幼托儿童所占的比例最多,分别为50.28%和42.53%;共报告实验室确诊重症病例53例,重症发生率为0.29%;有明显的季节分布,发病高峰期主要集中在5~7月;新疆手足口病以Cox A16和EV71为主要病原,主要发生在乌鲁木齐市和伊犁哈萨克自治州等地区;共报告20起聚集性病例,均为幼托机构。结论新疆手足口病发病水平不高,但存在明显的地区、人群和时间差异,建议在继续做好全面防控的同时,加强幼托机构的防控工作。 Objective To analyze the epidemiological characteristics and pathological changes of HFMD in Xinjiang from 2009 to 2011 and provide a scientific basis for the control of HFMD. Methods Direct reports of hand, foot and mouth disease reported from 2009-01-01 / 2011-12-31 in Xinjiang were derived from Chinese disease prevention and control information system, and descriptive epidemiological methods were used to analyze reported cases of hand, foot and mouth disease . Results The total number of HFMD cases in Xinjiang during the three years from 2009 to 2011 was 18 184, of which 1 648 were laboratory diagnoses, accounting for 8.95% of the total. The overall incidence was 28.10 per 100,000. Among the reported cases of hand foot and mouth disease in Xinjiang in 3 years, Urumqi City (5596 cases) continued to rank first in the list; while the first place in the laboratory diagnosis cases was Urumqi City (629 cases). The reported cases were mainly concentrated in the age group of 0-5 years (16,236 cases), accounting for 89.29% of the total cases, with men being higher than those of women; the proportion of scattered children and preschool children was the highest (50.28% and 42.53% respectively). Reported a total of 53 cases of laboratory confirmed severe cases, the incidence of severe disease was 0.29%; there is a clear seasonal distribution, the peak incidence of the disease mainly concentrated in May to July; Xinjiang foot and mouth disease Cox A16 and EV71 as the main pathogen, mainly in Urumqi and Yili Kazak Autonomous Prefecture and other regions; a total of 20 cases of aggregation were reported, are kindergartens. Conclusion The incidence of hand, foot and mouth disease in Xinjiang is not high, but there are obvious differences in regions, populations and time. It is suggested that the prevention and control of child care institutions should be strengthened while continuing to be well controlled.
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