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为观察乌拉地尔（ＵＲＡ）预防高血压患者拔管心血管副反应，对２４例高血压患者在全麻后拔管期间应用乌拉地尔抑制心血管应激效应。结果表明：拔管前静注ＵＲＡ１５ｍｇ的患者（ＵＲＡ组），ＳＢＰ、ＤＢＰ、ＨＲ、ＲＰＰ在拔管期间与对照值相比较变化不明显。未用ＵＲＡ的患者（对照组），各观察值在拔管期间与对照值相比较增高显著（Ｐ＜０．０１）。两组比较差异有显著性（Ｐ＜０．０１）。说明拔管前静注ＵＲＡ１５ｍｇ能有效抑制高血压患者因拔管引起的心血管应激效应。
To observe the URA prevention of extubation in hypertensive patients with cardiovascular adverse reactions, 24 patients with hypertension in extubation after urapidil administration of cardiovascular stress suppression. The results showed that SBP, DBP, HR and RPP did not change significantly compared with the control group during extubation in patients with URA15mg (URA group) before extubation. In patients without URA (control group), the observations increased significantly during the extubation compared with the control (P <0.01). There was significant difference between the two groups (P <0.01). Intravenous URA15mg before extubation can effectively inhibit cardiovascular stress caused by extubation in hypertensive patients.