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目的:探析尿激酶(UK)对急性脑梗死溶栓治疗的疗效及安全性。方法:对85例急性脑梗死患者随机分成溶栓组和对照组。溶栓组给予UK 150万U,在30~40 min内静脉滴注,随后的治疗同对照组。对照组采用通常的治疗方法。结果:溶栓组的神经功能改善、日常生活活动能力与对照组比较均有明显改善,两组病死率无统计学差异。结论:早期使用UK对脑梗死的治疗比常规治疗起效快、效果好,相对安全。
Objective: To investigate the efficacy and safety of urokinase (UK) in thrombolytic therapy of acute cerebral infarction. Methods: 85 patients with acute cerebral infarction were randomly divided into thrombolytic group and control group. Thrombolytic group given UK 1.5 million U, intravenous infusion within 30 ~ 40 min, followed by treatment with the control group. Control group using the usual treatment. Results: The thrombolysis group improved the neurological function, and the activities of daily living were significantly improved compared with the control group. There was no significant difference in mortality between the two groups. Conclusion: The early use of UK on cerebral infarction treatment than the rapid onset of effective, effective, relatively safe.