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肌病性上睑下垂(myopathic ptosis,MP)是由于影响了提上睑肌或其神经肌肉连接所引起。其它辅助提上睑的肌肉是M(?)ller氏平滑肌。作者局部应用萘甲唑啉(naphazoline)试图选择性地增加M(?)ller氏肌的收缩力,缓解肌病性上睑下垂。 研究的12例MP病人中,男5例,年龄18～72岁。肌强直性营养不良(myotonic dystrophy)3例;常染色体显性遗传性眼咽肌营养不良(oculopharyngeal muscular dystrophy)的同胞3人;重症肌无力5例;以上睑下垂、眼麻痹、肌病、神经病、白质脑病和胃肠功能障碍为特征的多系统线粒体病(MNGIE综合征)1例。17只下垂眼每只滴入0.1％
Myopathic ptosis (MP) is caused by affecting the levator muscle or its neuromuscular connections. Other muscles that help lift the upper eyelid are M (?) Ller’s smooth muscle. The authors applied naphazoline topically to try to selectively increase the contractile force of M? ¨ ller muscle and relieve myoplasmic ptosis. Of the 12 MP patients studied, 5 were men, aged 18 to 72 years. 3 myotonic dystrophy; 3 sibs with autosomal dominant oculopharyngeal muscular dystrophy; 5 with myasthenia gravis; 4 with ptosis, ocular paralysis, myopathy, neuropathy , Leukoencephalopathy and gastrointestinal dysfunction characterized by multi-system mitochondrial disease (MNGIE syndrome) in 1 case. 17 drooped eyes drip each 0.1%