本文用电刺激方法观察隔区镇痛规律,并探讨隔区镇痛与中央灰质(PAG)阿片受体的关系。在52只家兔中刺激了56个刺激点,结果表明:35个点有镇痛作用(占62％),6个点有易化作用(加强痛反应),15个点无效。刺激隔区的镇痛效应随刺激次数增多而增加,停止刺激后,尚有后作用,隔区的镇痛效应可被中脑中央灰质内微量注射纳洛酮(2μg/2μl)对抗,提示与中央灰质内阿片受体有关。 In this article, we used electrical stimulation to observe the analgesic rules of septal area and explored the relationship between septal analgesia and central opioid receptor (PAG). Fifty-six stimuli were stimulated in 52 rabbits. The results showed that analgesic effect was found in 35 points (62%), facilitated in 6 points (pain reaction was enhanced), and 15 points were not effective. The analgesic effect of the stimulation septum increased with the increase of the number of stimulation. After the stimulation was stopped, there was a posterior effect. The analgesic effect of the septal area could be antagonized by microinjection of naloxone (2μg / 2μl) in the central gray matter of midbrain, Central gray matter opioid receptors.