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目的旨在探讨颈动脉粥样硬化病变的性质和程度与冠状动脉粥样硬化病变的性质和程度之间的关系。方法2007年间西南医院心内科住院拟诊为冠心病入院进行冠状动脉造影者200例,根据冠脉造影结果按Gensini评分标准分为冠脉无病变组、轻度病变组及严重病变组。所有入选患者均进行颈动脉血管超声检测,测定颈动脉内膜一中层厚度(IMT)、颈总动脉内径并进行斑块积分,计算斑块发生例/率。结果冠脉病变组颈动脉IMT、斑块积分及斑块发生率较无病变组明显增大,且随着冠脉病变情况加重而增加,组间差异有统计学意义(P<0.05)。冠脉轻度病变组和无病变组的颈总动脉内径差异无统计学意义(P>0.05)。而随着冠脉病变加重,冠脉严重病变组的颈总动脉内径较冠脉轻度病变组和无病变组明显增大。结论颈动脉IMT、斑块积分及斑块发生率的改变与冠状动脉病变密切相关。
The purpose is to investigate the relationship between the nature and extent of carotid atherosclerosis and the nature and extent of coronary atherosclerotic lesions. Methods In 2007, 200 cases of coronary angiography were admitted to Department of Cardiology, Southwest Hospital of Cardiovascular Diseases. According to the results of coronary angiography, they were divided into coronary non-lesion group, mild lesion group and severe lesion group according to Gensini score. All selected patients were examined by carotid artery ultrasound, carotid artery intima-media thickness (IMT), carotid artery diameter and plaque score, plaque count / rate. Results The carotid artery IMT, plaque score and plaque incidence in coronary artery disease group were significantly higher than those in non - disease group, and increased with the severity of coronary artery disease. The difference between the two groups was statistically significant (P <0.05). There was no significant difference in the diameter of common carotid artery between mild coronary lesion and non-lesion (P> 0.05). With the aggravation of coronary artery disease, the diameter of common carotid artery in severe coronary artery disease group was significantly higher than that in mild coronary lesion group and non-lesion group. Conclusion The changes of carotid IMT, plaque score and plaque incidence are closely related to coronary artery disease.