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[目的]观察国产及进口雷帕霉素洗脱支架对冠心病合并糖尿病的治疗效果。[方法]187例冠心病合并糖尿病患者,Cypher(进口)支架组89例,Firebird(国产)支架组98例,均成功进行PCI。两组患者术后均正规应用抗凝、抗血小板及调治治疗。随访6～12个月,观察并记录再狭窄、主要心血管事件(泵衰竭、急性心肌梗死)、心脏性猝死等心脏事件。[结果]6～12月中Cypher支架组发生su心脏性猝死1例,急性心肌梗死0例,2例泵衰竭;其中50例复查冠状动脉造影发现支架再狭窄3例,占6.0%。Firebird支架组发生心脏性猝死1例,急性心肌梗死1例,2例泵衰竭;其中54例复查冠状动脉造影发现支架再狭窄4例,占7.4%。Cypher支架组与Firebird支架组6～12月内主要终点事件发生率相似。[结论]Cypher支架组与Firebird支架组对糖尿病合并冠心病的患者效果无明显差异。
[Objective] To observe the therapeutic effect of domestic and imported rapamycin-eluting stents on coronary heart disease complicated with diabetes. [Method] A total of 187 patients with coronary heart disease and diabetes, including 89 Cypher stent and 98 Firebird stent were successfully performed PCI. Two groups of patients were formally applied anticoagulant, anti-platelet therapy and treatment. Followed up for 6 to 12 months, observed and recorded restenosis, major cardiovascular events (pump failure, acute myocardial infarction), sudden cardiac death and other cardiac events. [Results] One case of sudden cardiac death, one case of acute myocardial infarction, and two cases of pump failure occurred in the Cypher stent group from June to December. Among them, 50 cases underwent repeat coronary angiography to find stent restenosis in 3 cases (6.0%). Firebird stent group occurred in 1 case of sudden cardiac death, 1 case of acute myocardial infarction, 2 cases of pump failure; of which 54 cases of coronary angiography coronary stent restenosis found in 4 cases (7.4%). The incidence of primary endpoint events between 6 and 12 months in the Cypher Stent group and the Firebird Stent group was similar. [Conclusion] There is no significant difference between Cypher stent group and Firebird stent group on patients with diabetes mellitus and coronary heart disease.