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目的探讨鼻腔鼻窦畸胎癌肉瘤的临床病理特征、病理诊断及鉴别诊断要点,提高对该肿瘤的认识。方法对我院收治的2例鼻腔鼻窦畸胎癌肉瘤患者临床资料,采用免疫组织化学标记,在显微镜下观察组织学形态及免疫组化表达。结果临床表现主要为反复鼻塞、出血及头痛,检查为鼻腔息肉样新生物,病理诊断镜下可见畸胎瘤的三个胚层的组织,在此基础上同时出现癌肉瘤的成份。随访2例肿瘤均复发。结论鼻腔鼻窦畸胎癌肉瘤是一种具有畸胎瘤和癌肉瘤特征的罕见恶性肿瘤,取材应充分,以免误诊和漏诊。
Objective To investigate the clinicopathological characteristics, pathological diagnosis and differential diagnosis of nasal sinuses with teratocarcinoma and to improve the understanding of this tumor. Methods The clinical data of 2 cases of nasal sinuses with teratocarcinoma of the sarcoma admitted to our hospital were observed by immunohistochemistry with immunohistochemistry. The histological morphology and immunohistochemical expression were observed under the microscope. Results The main clinical manifestations of repeated nasal congestion, bleeding and headache, check for nasal polyps like new organisms, pathological diagnosis of teratoma three germinal tissue, microscopic appearance of carcinoid at the same time on the basis of ingredients. Follow-up 2 cases of tumor recurrence. Conclusion Nasal sinus teratoma Carcinosarcoma is a rare malignant tumor characterized by teratoma and carcinosarcoma. The material should be sufficient to avoid misdiagnosis and missed diagnosis.