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目的分析老年肺部感染合并心功能不全患者行硝酸甘油微泵的安全性与有效性,为临床治疗提供参考。方法选取医院2014年2月-2015年4月收治老年肺部感染合并心功能不全患者56例为研究对象,随机为研究组和对照组各28例,对照组患者采取吸氧、控制感染、利尿等治疗,研究组患者在此基础上采取硝酸甘油微泵治疗,分析两组患者治疗效果。结果研究组患者治疗总有效率91.1%,显著高于对照组75.0%(P<0.05),治疗前,两组患者PaO_2/FiO_2和CVP差异无统计学意义,治疗后研究组PaO_2/FiO_2(269.34±41.28)显著高于对照组(208.16±49.67)(P<0.05),研究组CVP(8.92±2.54)cmH_2O显著低于对照组(11.06±2.25)cmH_2O(P<0.05);研究组住院时间、肺部啰音减少时间等显著短于对照组(P<0.05),研究组BNP恢复正常时间(2.89±1.28)d显著少于对照组(5.23±1.49)d(P<0.05);研究组1例出现头晕症状,调整硝酸甘油剂量后好转。结论老年肺部感染并心功能不全患者治疗中,采用硝酸甘油微泵治疗能够提高治疗效果,不良反应小,具有推广价值。
Objective To analyze the safety and efficacy of nitroglycerin micropump in aged patients with pulmonary infection complicated with cardiac insufficiency and to provide reference for clinical treatment. Methods Fifty-six patients with senile pulmonary infection complicated with cardiac insufficiency from February 2014 to April 2015 in our hospital were randomly divided into study group and control group with 28 cases in each group. Patients in control group were treated with oxygen inhalation, infection control, diuretic On the basis of this study, patients in the study group took nitroglycerin micro-pump therapy and analyzed the therapeutic effect of the two groups of patients. Results The total effective rate of the study group was 91.1%, significantly higher than that of the control group 75.0% (P <0.05). There was no significant difference in PaO_2 / FiO_2 and CVP between the two groups before treatment, PaO_2 / FiO_2 (269.34 ± P <0.05). The CVP (8.92 ± 2.54) cmH_2O in the study group was significantly lower than that in the control group (11.06 ± 2.25) cmH_2O (P <0.05). The length of hospital stay, (P <0.05). The BNP recovery time (2.89 ± 1.28) d in the study group was significantly shorter than that in the control group (5.23 ± 1.49) d (P <0.05). The study group 1 Cases of dizziness symptoms, improve the dose of nitroglycerin improved. Conclusion In elderly patients with pulmonary infection and cardiac insufficiency, nitroglycerin micro-pump therapy can improve the treatment effect, with small adverse reactions, with the promotion of value.