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目的通过对唇腭裂患者的血象进行回顾性分析,探讨患儿血象各项参数的变化,为确定患儿真假感染、能否手术提供有针对性的建议和依据。方法选择2010年-2014年来邯郸市中心医院住院治疗的1095例唇腭裂患者的血象进行回顾性分析,以健康体检者500例作为对照。结果各年龄段唇腭裂组与健康对照组白细胞、红细胞和血小板计数有显著差异,而血红蛋白浓度之间没有显著差异。结论唇腭裂患儿由于口腔生理解剖结构缺陷更易患病毒感染或急、慢性炎症,表现为血象中一些参数的异常,可能会对麻醉和手术有一定影响。因此,对于唇腭裂患儿应该更加慎重的选择手术适应症。
Objective To retrospectively analyze the blood images of patients with cleft lip and palate, to explore the changes of blood parameters in children, to provide targeted advice and basis for determining the true and false infection in children. Methods From 2010 to 2014, 1095 cases of cleft lip and palate hospitalized in Handan Central Hospital were retrospectively analyzed, and 500 healthy subjects were used as control. Results Leukocytes, erythrocytes and platelet counts were significantly different among cleft lip and palate patients and healthy controls at all ages, but there was no significant difference between hemoglobin concentrations. Conclusion Children with cleft lip and palate are more susceptible to viral infection or acute and chronic inflammation due to oral physiological anatomical defects. Some abnormalities in blood parameters may have an impact on anesthesia and surgery. Therefore, children with cleft lip and palate should be more careful selection of surgical indications.