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目的:对解热镇痛消炎药的不良反应(ADRs)监察与临床用药问题进行分析。方法:由解热镇痛消炎药诱发的ADRs病例,按器官/系统分类、症状严重程度分级。对本组ADRs病例的诱发药物、症状表现、严重程度、转归以及临床ADRs的监察与用药进行分析讨论。结果:本院ADRs病例中由解热镇痛消炎药诱发者71例,91例次,占全部ADRs病例中的16.9%,ADRs造成损害中重度者达43.6%,症状表现涉及11个器官/系统类型,诱发药物涉及24个品种,治愈59例,好转9例,有后遗症3例。结论:本文强调应熟悉解热镇痛消炎药的组方与性能,避免误用或重复用药;应了解患者曾用药情况和ADRs发生史;高度重视儿童用药的ADRs问题;慎用中药注射剂,并应加强对解热镇痛消炎药ADRs的监察与防治
OBJECTIVE: To monitor the adverse reactions (ADRs) of antipyretic and analgesic anti-inflammatory drugs and clinical medication problems. Methods: ADRs induced by antipyretic analgesic anti-inflammatory drugs were classified according to organ / system classification and severity of symptoms. In this group of ADRs induced drugs, symptoms, severity, prognosis and clinical ADRs monitoring and medication analysis and discussion. Results: Among the ADRs in our hospital, 71 cases were induced by antipyretic and analgesic anti-inflammatory drugs, 91 cases, accounting for 16.9% of all cases of ADRs. The ADRs caused 43.6% A total of 24 organs were involved in the induction of drug, 59 cases were cured, 9 cases improved, and 3 cases had sequelae. CONCLUSIONS: This article emphasizes that patients should be familiar with the prescription and performance of antipyretic and analgesic anti-inflammatory drugs to avoid misuse or repeated medication; patients should be aware of previous drug use and history of ADRs; attach great importance to ADRs in children; caution with traditional Chinese medicine injections and Should strengthen the anti-inflammatory analgesic ADRs monitoring and prevention