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目的 研究丙型、庚型肝炎病毒 (HCV、HGV )母婴传播及其影响因素。方法 2 0 0 0年 1月至 2 0 0 2年12月应用第三代ELISA法检测HCV -Ab、HGV -Ab ,FQ -PCR方法检测HCV -RNA、HGV -RNA。结果 2 0 52例普通孕妇检测抗HCV阳性 2 2例 ,阳性率 1 0 7% ,其中 16例HCVRNA阳性母亲所生 16例婴儿有 3例HCVRNA阳性 ,母婴传播率为 18 75%。 3 18例普通孕妇检测抗HGV阳性 8例 ,阳性率 2 52 % ,其中 4例HGVRNA阳性母亲所生 4例婴儿 1例HGVRNA阳性。结论 阴道分娩过程感染可能是HCV、HGV母婴传播主要途径 ,孕妇临产时ALT升高是孕妇母婴传播的危险因素
Objective To study the transmission of hepatitis C and hepatitis G virus (HCV, HGV) and its influencing factors. Methods From January 2000 to December 2002, HCV-Ab, HGV-Ab and FQ-PCR methods were used to detect HCV-RNA and HGV-RNA by the third generation ELISA method. Results Twenty-two 52 cases of common pregnant women detected 22 positive cases of HCV, the positive rate was 10.7%. Of 16 cases, 16 cases of HCVRNA-positive mothers had HCVRNA positive and the mother-to-infant transmission rate was 18 75%. Among 18 cases of normal pregnant women, 8 cases were detected positive for anti-HGV, the positive rate was 52.5%. One case of HGV RNA positive was found in 4 infants of 4 HGV RNA positive mothers. Conclusions Infection during vaginal delivery may be the main route of mother-to-child transmission of HCV and HGV. Increasing ALT during labor is a risk factor for mother-to-child transmission of pregnant women