该文介绍了斑马鱼模型的特点及其在中药毒性靶器官研究中的应用,重点介绍了在急性毒性、肝脏毒性、心血管毒性、肾脏毒性和神经毒性研究等方面的应用,系统分析了斑马鱼这一新型模式动物在中药毒性靶器官研究中的优势及其独特价值,以期为推动中药毒性研究与安全性评价提供新的思路与方法。 This paper introduces the characteristics of zebrafish model and its application in the study of toxic target organ of traditional Chinese medicine. The application of zebrafish model in the research of acute toxicity, hepatotoxicity, cardiovascular toxicity, nephrotoxicity and neurotoxicity is mainly introduced. The zebra The advantages and unique values ​​of fish, a new model animal, in the study of toxic target organ of traditional Chinese medicine, with a view to providing new ideas and methods for promoting the toxicity study and safety evaluation of traditional Chinese medicine.