目的了解烧伤外科患者创面金黄色葡萄球菌感染与定植情况,为制定防控措施提供参考。方法通过临床观察和细菌分离鉴定,对某医院烧伤外科住院烧伤患者创面感染病原菌和临床特征进行调查。结果调查期间从该医院烧伤科患者创面分泌物标本中分离出金黄色葡萄球菌112株,其中耐甲氧西林菌株(MRSA)占77.68%。烧伤患者创面多呈现深度创面和难愈性创面,造成长时间住院,接受多种侵入性操作,常伴有基础疾病和生理指标异常,且使用抗菌药物。患者住院时间>30 d、至少有一项生理指标异常、有近期侵袭性操作是创面MRSA定植和感染的危险因素。结论烧伤外科患者创面检出MRSA主要是接触感染和定植,致创面经久不愈,应采取针对性的防控措施。 Objective To understand the infection and colonization of Staphylococcus aureus in the wounds of burn patients and provide references for the development of prevention and control measures. Methods By clinical observation and bacterial isolation and identification, pathogenic bacteria and clinical features of wound infection in burn hospitalized burn patients in a hospital were investigated. Results During the investigation, 112 strains of Staphylococcus aureus were isolated from the wound secretions of patients in the hospital’s burn department, of which methicillin-resistant strains (MRSA) accounted for 77.68%. Burn wounds mostly show deep wounds and refractory wounds, resulting in prolonged hospitalization, accepting multiple invasive procedures, often accompanied by abnormalities in underlying diseases and physiological indicators, and the use of antimicrobial agents. Patients hospitalized for> 30 d, at least one physiological index abnormalities, the recent invasive operation is wound MRSA colonization and infection risk factors. Conclusion The wounds detected in surgical patients with burn wounds are mainly caused by contact infection and colonization, which leads to prolonged unhealed wounds. Therefore, targeted prevention and control measures should be taken.