作者对末端脱氧核苷酰转移酶(简称TdT)的引物、底物及抑制剂等酶学性质进行了探讨,观察到TdT的引物、底物及酶浓度曲线与一般酶促反应动力学曲线基本相符,建立起稳定的酶测活系统。用于临床,对白血病患者外用血检测了TdT活性,结果表明急淋患者其活性明显高于急粒等其他类型的白血病患者。 The author of the end of deoxynucleotidyl transferase (TdT) primers, substrates and inhibitors and other enzymatic properties were discussed TdT primer, substrate and enzyme concentration curve and the general enzymatic reaction kinetics curve Consistent with the establishment of a stable enzymatic activity system. For clinical use, TdT activity was measured in peripheral blood of patients with leukemia. The results showed that the activity of TdT was significantly higher in patients with acute lymphoid leukemia than in other types of leukemia such as acute pellet.