论文部分内容阅读
小儿癫痫是常见的临床综合征,目前对癫痫发病机理的研究,以中枢神经介质方面进行者为多,也有研究微量元素与癫痫之间的关系者。为了探讨锌、铜与癫痫的关系,从1979年元月至1980年8月,我们对129例未经治疗的癫痫患儿作了血清锌、铜含量的测定,并对其中30例患儿在治疗前后测定了血清锌、铜、钙、镁含量,以了解抗癫痫药物对这四种元素代谢的影响,现将结果分析如下。资料和方法一、临床资料:129例癫痫患儿中,男85例,女44例。初诊时年龄在3岁以下者5例,～6岁26例,～9岁41例,～12岁46例,12岁以上的11例。本组患儿均有一年以上的癫痫发作史。临床类型属于大发作者68例,限局性运动性发作22例,小发作12例,精神运动型11例,混合型7例,头痛型5例,小运动型3例,肌阵挛与腹痛性癫痫各1例。129例中有84例曾作脑电图检查,结果69例患儿的脑电图符合癫痫的异常改变,正常者15例。二、实验方法:血清锌、铜、钙、镁的测定,采用原子吸收分光光谱法,固定专人操
Pediatric epilepsy is a common clinical syndrome, the current study of the pathogenesis of epilepsy, to the central nervous system as much, there are also studies of the relationship between trace elements and epilepsy. In order to explore the relationship between zinc, copper and epilepsy, from January 1979 to August 1980, we measured serum zinc and copper in 129 children with untreated epilepsy and 30 of them Determination of serum zinc, copper, calcium and magnesium levels before and after treatment in order to understand the antiepileptic drugs on the four elements of metabolism, the results are as follows. Materials and Methods First, the clinical data: 129 cases of epilepsy in children, 85 males and 44 females. Five patients were under 3 years of age at initial diagnosis, 26 at age 6, 41 at age 9, 46 at age 12, and 11 at 12 years of age. This group of children have more than one year history of seizures. Clinical types belong to the Daihatsu 68 cases, 22 cases of limited seizure motility, 12 cases of small seizures, psychomotor 11 cases, mixed 7 cases, headache 5 cases, 3 cases of small sports, myoclonus and abdominal pain Epilepsy in 1 case. Eighteen of the 129 patients had an EEG examination, the results of 69 cases of children with EEG abnormal changes in epilepsy, normal in 15 cases. Second, the experimental methods: Determination of serum zinc, copper, calcium and magnesium, using atomic absorption spectrometry, fixed expert exercises