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目的 :观察丹参注射液治疗急性高血压脑出血的疗效。方法 :3 0例急性高血压脑出血 (幕上出血≥3 0 m l,小脑出血≥ 10 ml,脑干出血≥ 5 ml)患者随机分为 2组。丹参组 ( 15例 )在西药常规治疗基础上加用丹参注射液 16ml加入 5 %葡萄糖 5 0 0 m l静滴 ,每日 1次 ,连用 14日 ,观察 2 8日 ;对照组只给予西药常规治疗。比较 2组疗效。结果 :丹参组总有效率 ( 80 .0 % )优于对照组 ( 3 3 .3 % ) ,P<0 .0 1;丹参组病死率 ( 13 .3 % )低于对照组 ( 5 3 .3 % ) ,P<0 .0 1。丹参组治疗 14日颅脑 CT复查血肿平均吸收率 ( 66.2 % )明显优于对照组 ( 3 3 .7% ) ,P<0 .0 1,2组治疗前后血肿差值〔( 2 9.95± 5 .4 4) ml和 ( 13 .5 7± 3 .70 ) m l〕比较有非常显著性差异 ( P<0 .0 1)。丹参组治疗后心电图及血粘度也有改善。 2组均无再出血或血肿扩大。结论 :在西医常规治疗基础上加用丹参注射液治疗急性高血压脑出血疗效较好 ,值得进一步研究
Objective: To observe the therapeutic effect of Danshen injection on acute hypertensive intracerebral hemorrhage. Methods: Thirty patients with acute hypertensive intracerebral hemorrhage (supratentorial hemorrhage ≥ 300 mm, cerebellar hemorrhage ≥ 10 ml, and brainstem hemorrhage ≥ 5 ml) were randomly divided into two groups. Radix Salviae Miltiorrhizae group (n = 15) was given routine treatment of western medicine with Danshen injection (16ml) and 5% dextrose (500ml) intravenously once daily for 14 days for 28 days. The control group was given conventional western medicine . Compare 2 groups curative effect. Results: The total effective rate (80.0%) in Salvia miltiorrhiza group was better than that in control group (33.3%), P <0.01; the mortality in Salvia miltiorrhiza group was lower than that in control group (53.3%). 3%), P <0. The average rate of hematoma absorption (66.2%) in Danshen group on 14th was significantly better than that in control group (33.7%), P <0. .4 4) ml and (13.57 ± 3.70) ml〕 had a very significant difference (P <0.01). Salvia group ECG and blood viscosity after treatment also improved. No re-bleeding or hematoma enlargement in the two groups. Conclusion: The treatment of acute hypertensive intracerebral hemorrhage with salvia miltiorrhiza injection on the basis of routine treatment of western medicine is effective and worthy of further study