论文部分内容阅读
应用TDx快速血药浓度监测仪对727份血样进行测定及分析。结果显示，血药浓度在有效范围内的仅占31．64％，而有68．36％患者的血浓低于或高于有效浓度范围，造成临床治疗无效或出现毒副作用。经调整用药剂量，病情得以迅速改善。表明对于有效药物浓度狭窄、治疗指数低的药物进行血药浓度监测，对指导临床用药，提高临床疗效有很大意义。
727 blood samples were measured and analyzed with TDx rapid plasma concentration monitor. The results showed that plasma concentrations in the effective range of only 31.64%, while 68.36% of patients with blood concentration is lower than or higher than the effective concentration range, resulting in clinical treatment ineffective or toxic side effects. After adjusting the dosage, the condition can be rapidly improved. It shows that for the effective drug concentration is narrow, the therapeutic index of low blood drug concentration monitoring, to guide clinical medication, improve clinical efficacy of great significance.