具有酸性或碱性的有机药物是比较普遍的。在1963年版中国药典中占58％(包括它们的盐)这些药物很多在临床上占较重要的地位:抗菌素中青霉素、链霉素、四环素、土霉素及庆大霉素,强力霉素等常用药物以及极大多数其他抗菌素都具有酸性或碱性。磺胺药物中如磺胺嘧啶,磺胺脒;巴比妥类药物,局麻药,抗过敏药,一部份维生素,如抗坏血酸,盐酸硫胺,菸酸及几乎全部生物碱也都是具有酸性或碱性的药物。所以药物酸碱性是有机药物比较重要的性质。 Organic acids that are acidic or basic are more common. In the 1963 edition of the Chinese Pharmacopoeia 58% (including their salts) many of these drugs clinically important role: penicillin antibiotics, streptomycin, tetracycline, oxytetracycline and gentamicin, doxycycline, etc. Commonly used drugs and most other antibiotics are acidic or alkaline. Sulfa drugs such as sulfadiazine, sulfanilamide; barbiturates, local anesthetics, anti-allergy drugs, some vitamins, such as ascorbic acid, thiamine hydrochloride, niacin and almost all alkaloids are also acidic or alkaline Drug. Therefore, the pharmaceutical acid-base is more important organic drugs properties.