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目的研究妊娠期接受手机辐射对仔鼠学习记忆的影响。方法孕鼠经不同强度手机辐射后,测定新生鼠脑组织乙酰胆碱酯酶(AChE)活力,应用Morris水迷宫测试幼鼠学习记忆能力。结果与对照组比较,AChE活力升高,其中高、中强度辐射组(0.55±0.20)、(0.51±0.14)U/mgprot与对照组(0.33±0.22)U/mgprot比较,差异有统计学意义(P<0.05);定位航行实验,第2、3d,高、中强度辐射组平均潜伏期分别为(63.9±12.2)、(66.6±20.4)和(55.1±20.5)、(53.3±16.8)s,与对照组(36.2±13.6)、(32.9±16.5)s比较,明显延长,差异有统计学意义(P<0.05),第4 d,各辐射组平均潜伏期均长于对照组,差异有统计学意义(P<0.05);高强度辐射组穿越原平台区次数低于对照组,差异有统计学意义(P<0.05)。结论妊娠期接受手机辐射对仔鼠学习记忆能力有一定损害。
Objective To study the influence of cellphone radiation during pregnancy on learning and memory in offspring. Methods The pregnant rats were exposed to different intensities of cell phone radiation to measure acetylcholinesterase (AChE) activity in brain tissue of newborn rats. Morris water maze test was used to study the ability of learning and memory in young rats. Results Compared with the control group, the activity of AChE increased, and there was significant difference between high and medium intensity radiation group (0.55 ± 0.20), (0.51 ± 0.14) U / mgprot and control group (0.33 ± 0.22) U / mgprot (P <0.05). In the navigation experiment, the average latency of high and medium intensity radiation groups were (63.9 ± 12.2), (66.6 ± 20.4) and (55.1 ± 20.5) and (53.3 ± 16.8) Compared with the control group (36.2 ± 13.6), (32.9 ± 16.5) s, the difference was statistically significant (P <0.05). On the 4th day, the average latency of each radiation group was longer than that of the control group, the difference was statistically significant (P <0.05). The number of high-intensity radiation group crossing the original platform area was lower than that of the control group (P <0.05). Conclusion The cellphone radiation during pregnancy has some damage to the ability of learning and memory in offspring.