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目的 :探讨甲亢病人胃泌素水平增高的临床意义。方法 :以放射免疫法测定 4 0例甲亢患者血清胃泌素水平并与手术后及正常人的水平相比较。结果 :正常人胃泌素水平为 75± 30 .6ng/L ,甲亢患者为 173± 70 .5ng/L ,两者相比有显著差异 (P<0 .0 1)。手术后胃泌素水平为 98± 18.4ng/L ,接近正常人水平。相关分析表明 ,胃泌素水平的增高与血清T3 、T4水平相平行 ,呈正相关关系 (P <0 .0 5 )。结论 :血清胃泌素水平可以作为甲亢患者实验室诊断及临床疗效观察的另一种指标。
Objective: To investigate the clinical significance of elevated gastrin levels in patients with hyperthyroidism. Methods: The levels of serum gastrin in 40 hyperthyroid patients were determined by radioimmunoassay and compared with those of postoperative and normal controls. Results: The normal gastrin level was 75 ± 30.6ng / L, and hyperthyroidism was 173 ± 70.5ng / L, there was a significant difference between the two groups (P <0.01). The gastrin level after operation was 98 ± 18.4ng / L, which was close to the normal level. Correlation analysis showed that gastrin levels increased in parallel with serum T3 and T4 levels (P <0.05). Conclusion: Serum gastrin levels can be used as another indicator of laboratory diagnosis and clinical curative effect of patients with hyperthyroidism.