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目的观察铝碳酸镁咀嚼片辅助奥美拉唑治疗成人活动期胃溃疡的临床效果。方法选取医院收治的活动期胃溃疡成年患者88例作为研究对象,随机分为研究组和对照组,每组44例。2组均给予克拉霉素、甲硝唑常规治疗,同时对照组给予奥美拉唑治疗,研究组在对照组基础上给予铝碳酸镁咀嚼片辅助治疗,比较2组患者治疗前后疼痛、溃疡面及临床疗效。结果治疗前2组患者上腹部疼痛评分、溃疡面大小比较差异无统计学意义(P>0.05);治疗后,研究组上腹部疼痛评分、溃疡面大小均显著低于对照组(P<0.01)。研究组治疗总有效率为97.73%高于对照组的84.09%(P<0.05)。结论铝碳酸镁咀嚼片辅助奥美拉唑在成人活动期胃溃疡中治疗可提高胃黏膜保护能力,从而协助提高疗效,具有显著临床治疗效果。
Objective To observe the clinical effect of aluminum magnesium carbonate chewable tablet on omeprazole in the treatment of adult active gastric ulcer. Methods Eighty-eight adult patients with active gastric ulcer admitted to hospital were selected as study subjects and randomly divided into study group and control group, with 44 cases in each group. The two groups were given clarithromycin, metronidazole routine treatment, while the control group was given omeprazole treatment group in the control group on the basis of aluminum magnesium carbonate chewable tablets adjuvant therapy, the two groups of patients before and after treatment of pain, ulcer surface And clinical efficacy. Results There was no significant difference in the upper abdominal pain scores and the ulcer surface between the two groups before treatment (P> 0.05). After the treatment, the pain scores and ulcer surface of the study group were significantly lower than those of the control group (P <0.01) . The total effective rate of the study group was 97.73% higher than that of the control group (84.09%, P <0.05). Conclusions The treatment of omeprazole assisted by omeprazole in adult active gastric ulcer can improve gastric mucosal protective ability, which can help to improve the curative effect and have significant clinical curative effect.