妊娠首三月使用皮质类固醇是否会增加先天性畸形的危险性尚无定论。本研究是以医院为基础进行的病例－对照研究及疾病监测。选１１４８名无已知综合征的口腔裂新生儿为病例组，将以下列３组人群作为对照组：与每个病例配对的新生儿（１１７３名）；同一医院内每个病例出生... Whether the use of corticosteroids in the first trimester of pregnancy increases the risk of congenital malformations is inconclusive. This study is a hospital-based case-control study and disease surveillance. A total of 1148 newborns with oral dehiscence without known syndrome were selected as the case group, and the following three groups of people were used as the control group: neonatal paired with each case (1173); each case born in the same hospital ...