近年来新生儿鼠伤寒沙门氏菌肠炎报道日趋增多,新生儿病情危重且病死率高。过去认为对此细菌敏感的抗生素。如庆大霉素、吡哌酸、氨基苄青霉素、红霉素及美西林等,目前治疗效果却不佳。我院自1987年3月～5月收治新生儿鼠伤寒沙门氏菌肠炎14例,应用我国生产的头孢噻肟钠治疗后,疗效满意。全部病例均有发热、精神萎靡、腹泻、脓血 In recent years, neonatal Salmonella typhimurium enteritis is reported increasing, critically ill newborns and high mortality. Antibiotics used to be sensitive to this bacterium. Such as gentamicin, pipemidic acid, ampicillin, erythromycin, and the United States Xilin, the current treatment is not good. In our hospital from March 1987 to May were treated neonatal Salmonella typhimurium enteritis 14 cases, the application of cefotaxime sodium produced in our country, the curative effect is satisfactory. All cases have fever, apathetic, diarrhea, pus and blood