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糖尿病控制不佳常伴生长激素(growth hormone,GH)水平增高,本文研究GH水平增高对糖尿病代谢紊乱的重要性。方法和结果Ⅰ型糖尿病人12(男2,女10)例,平均年龄15±1岁,研究前正采用常规胰岛素注射治疗。静脉插管每小时取血测定血糖、GH、生长激素介质C(somatomedin C),随即改用胰岛素泵治疗,7天后复查上述指标。胰岛素泵治疗前、后24小时血糖平均值分别为208±22和119±15mg/dl(P<0.001);24小时GH平均值分别为17±3和9±2ng/ml(P<0.001);空腹生长激素介质C水平分别为1.09±0.26和1.67±0.25U/ml(P<0.005)。另一研究为Ⅰ型糖尿病人14(男4,女10)例,
Poor control of diabetes often accompanied by increased levels of growth hormone (GH), the paper studies the importance of elevated GH levels on the metabolic disorders of diabetes. Methods and Results Type I diabetes 12 (male 2, female 10) patients, mean age 15 ± 1 years old, before the study is using conventional insulin injections. Blood samples were taken from the venous cannula for blood glucose, GH and somatomedin C, and then switched to insulin pump for treatment. The above indexes were reviewed after 7 days. The average blood glucose level at 24 hours before and after insulin pump was 208 ± 22 and 119 ± 15 mg / dl, respectively (P <0.001). The average 24 h GH was 17 ± 3 and 9 ± 2 ng / ml respectively (P <0.001) Fasting growth hormone medium C levels were 1.09 ± 0.26 and 1.67 ± 0.25 U / ml, respectively (P <0.005). Another study was type I diabetes 14 (male 4, female 10) cases,