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目的观察甲波尼龙抢救治疗双硫仑样反应的快速效应及安全性。方法将我院2010.5-2011.10急救治疗的69例双硫仑反应患者随机分为治疗组和对照组。治疗组用甲波尼龙(简称甲强龙)80mg加生理盐水100ml静脉滴注;对照组给予等效剂量的地塞米松针15mg加生理盐水100ml静脉滴注。两组其他一般性基础治疗相同,观察用药后两组症状缓解快慢。结果治疗组(甲强龙组)缓解症状较对照组症状(地塞米松组)快,无明显副作用。结论甲强龙抢救治疗双硫仑样反应见效快,不良反应少,安全可靠,值得临床医生推广使用。
Objective To observe the rapid response and safety of methamphetamine in the treatment of disulfiram-like reaction. Methods A total of 69 patients with disulfiram response who were treated in our hospital from May 2010 to May 2011 were randomly divided into treatment group and control group. In the treatment group, 80 mg of methionine (abbreviated as methylprednisolone) and 100 ml of saline were intravenously dripped. In the control group, an equivalent dose of dexamethasone needle (15 mg) and saline (100 ml) were given intravenously. The other two groups of other basic treatment of the same general observation of the two groups after treatment to alleviate the speed of symptoms. Results The treatment group (methylprednisolone group) relieved symptoms faster than the control group symptoms (dexamethasone group), no obvious side effects. Conclusion The treatment of methylprednisolone disulfiram-like response quick, less adverse reactions, safe and reliable, it is worth to promote the use of clinicians.