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目的 :观察血清CD11b/CD18、CD5 4在脑梗死急性期的变化。方法 :采用流式细胞仪测定 3 0例脑梗死患者急性期和 2 0例健康对照组血清CD11b/CD18、CD5 4的含量。结果 :脑梗死急性期患者血清CD11b/CD18、CD5 4含量明显增高 ,与正常对照组相比较 ,差异有显著性 ;轻、中、重 3型脑梗死患者血清CD11b/CD18、CD5 4含量明显不同。结论 :脑梗死急性期患者血清CD11b/CD18、CD5 4明显升高 ,且与病情轻重有关 ,病情越重 ,其水平越高。
Objective: To observe the changes of serum CD11b / CD18, CD5 4 in acute stage of cerebral infarction. Methods: Serum levels of CD11b / CD18 and CD54 in 30 acute cerebral infarction patients and 20 healthy controls were measured by flow cytometry. Results: Serum levels of CD11b / CD18 and CD54 in patients with acute cerebral infarction were significantly higher than those in the normal control group, while the levels of CD11b / CD18 and CD54 in patients with mild, moderate and severe type 3 cerebral infarction were significantly different . Conclusion: Serum levels of CD11b / CD18 and CD54 are significantly increased in patients with acute cerebral infarction, and are associated with the severity of illness. The more severe the disease is, the higher the level is.