用胺解法合成了N,N′-二丁氧基丙基二硫代二丙酰胺(BPD),产率85.6%,用IR和1HNMR对其结构进行了表征。对BPD进行了抑菌、杀藻性能考察,结果显示,BPD对金黄色葡萄球菌、大肠杆菌、裂殖酵母菌的最小抑菌质量浓度分别为0.0625、0.25、0.125g/L;对湛江叉边金藻24h和48h的半致死质量浓度分别为1.77mg/L和1.44mg/L。以BPD为防污剂制备了海洋防污涂料,173d的实海挂板结果较空白板仅有少量污损生物附着。 N, N’-dibutoxypropyl dithiodipropionamide (BPD) was synthesized by amineysis. The yield was 85.6%. Its structure was characterized by IR and 1HNMR. The antibacterial and algicidal properties of BPD were investigated. The results showed that the minimum inhibitory concentrations of BPD on Staphylococcus aureus, Escherichia coli and Schizosaccharomyces were 0.0625, 0.25 and 0.125 g / L, respectively. The median lethal concentrations of gold chlorella at 24h and 48h were 1.77mg / L and 1.44mg / L, respectively. Marine antifouling coatings were prepared with BPD as antifouling agent. The results of real sea hanging plate 173d were only a little fouling organisms attached to the blank board.