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目的 通过分析HIV抗体不确定结果及其带型进展情况,探讨预示HIV感染的意义和随访工作的重要性.方法 收集南宁市疾病预防控制中心实验室2012-2013年的78份HIV抗体不确定标本进行分析免疫印迹法(Western Blot,WB)条带的类型,并对24例个案患者进行了随访,观察WB条带的进展.结果 78份HIV抗体不确定标本中e删类共70份,gag类共7份,pol类1份.env类中gp160p24共39份,比例最大.24例随访的个案中,23例为env类型,20例转为HIV抗体阳性,3例条带无进展;还有1例随访个案为p17,1个月后也转为HIV抗体阳性.结论 env类型蛋白的不确定反应最为常见,预示着HIV感染性很大,特别是gp160p24.HIV抗体不确定若为HIV早期感染标志,应该尽早做好随访工作,及时进行诊断.“,”Objective To explore the importance of early HIV infection and follow-up work by analysis of indeterminate-re-sults HIV antibody.Methods Collected 78 cases of indeterminate HIV antibody from Nanning disease prevention and control center during 2012-2013,analyze the WB band features and the track results in the 24 cases.Results In 78 cases of indeterminate HIV antibodies,type env 70 cases,gag 7 cases,1 case of type pol.In all the env cases,39 cases of gp160p24 belt type,accounted for the highest proportion.Of 24 followed up cases,23 cases of type env,20 cases were converted into HIV antibody positive,3 cases with no progress;and 1 cases were followed up for p17,1 months after a follow-up to HIV antibody positive.Conclusion Of the indeterminate HIV antibody,type env protein was the most common,with adumbrative HIV infection,especially gp160p24.If indeterminate HIV antibody is HIV early signs of infection,should do the follow-up work as soon as possible and timely diagnosis.