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弥漫性嗜酸细胞性筋膜炎(DEF)于1975年首先由shulman报告,至今国外仅报告10几例,很少见。系统性硬皮病(ssD)伴发DEF更少见,最近作者遇见1例ssD伴发DEF的老年患者,现报告于下。女患,63岁。于1995年1月3日因四肢皮肤出现紧张感、肿胀、硬结和瘙痒;肢端发凉、手背微肿、大关节疼痛,四肢肌肉疼痛、无力、活动受限;左小腿、两侧前臂及大腿和躯干前面先后出现色素斑3年;出现吞噬困难和疼痛、周期性腹胀和便秘2年;近1年上述症状加重并出现体重下降和周围血象嗜酸细胞增多而入院。既往健康。无遗传和变态反应病
Diffuse eosinophilic fasciitis (DEF) first reported by shulman in 1975, so far only 10 reported cases abroad, it is rare. Systematic scleroderma (ssD) associated with DEF is less common, and the recent authors met with one case of elderly patients with ssD associated with DEF are reported below. Female suffering, 63 years old. On January 3, 1995 due to limbs skin tension, swelling, induration and itching; extremity cold, back of the hand swelling, joint pain, limb muscle pain, weakness, limited mobility; left leg, both forearms and Thigh and torso appeared in front of pigmented plaques for 3 years; phagocytic difficulties and pain, periodic bloating and constipation for 2 years; the past year, the above symptoms aggravated and weight loss and peripheral blood eosinophilia increased admission. Past health. No genetic and allergic disease