材料和方法 按适应症拔牙时切取小块龈组织标本117例,男50例,女67例,年龄17～75岁。标本经组织学检查无病变。按照国际统一的关于形体学、生理学和生物化学的年龄分组法,分4个年龄组:第1组17～21岁(青年)20例(男9,女11),第2组22～35岁(第一成年期)25例(男11,女14),第3组36～60岁(第二成年期)41例(男18,女23),第4组61～75岁(老年)31例(男12,女19)。因为口腔上皮细胞生物合成过程有明显的时间节 Materials and Methods 117 cases of small gingival tissue specimens were extracted from indications, including 50 males and 67 females, aged 17-75 years. Specimens histological examination without lesions. According to the internationally agreed age grouping method of physique, physiology and biochemistry, there are 4 age groups: group 1, 20 (male 9, female 11) 17 to 21 (youth), group 1 22 to 35 (Male 11, female 14), group 3 36 to 60 years old (second adult) 41 (male 18, female 23), group 4 61 to 75 (old) 31 Example (male 12, female 19). Because oral epithelial cell biosynthesis process has obvious time