近年来，头孢菌素类抗生素作为一类强有力的抗细菌感染药物，已被临床广泛应用，适用于许多单纯或混合感染。但因其化学结构类似青霉素，母核均含有不稳定的β－内酰胺环，易水解，其水溶液的不稳定性，放置时间越长则分解越多，不仅药效消失，而且产生的致敏物质也增多，因此? In recent years, cephalosporins antibiotics as a class of powerful antibacterial drugs, has been widely used in clinical, suitable for many simple or mixed infections. However, because of its chemical structure similar to penicillin, the mother nucleus contains unstable β-lactam ring, easy to hydrolyze, the instability of its aqueous solution, the longer the time it is decomposed more, not only the efficacy disappears, and the resulting sensitization Material also increased, so?