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冠状动脉粥样硬化性心脏病严重威胁人类的健康,脂联素(APN)与冠状动脉粥样硬化性心脏病密切相关。APN的基因多态性及其分泌部位的不同与冠状动脉粥样硬化性心脏病的发病相关。APN的血浆浓度可预测冠状动脉粥样硬化性心脏病及其预后。APN的抗炎及稳定斑块的作用可以治疗冠状动脉粥样硬化性心脏病。现就近年来国内外有关APN与冠状动脉粥样硬化性心脏病的预测,诊断及治疗的相关文献予以综述。
Coronary atherosclerotic heart disease is a serious threat to human health. Adiponectin (APN) is closely related to coronary heart disease. APN gene polymorphism and secretion of different parts of the coronary heart disease and coronary heart disease related. Plasma concentrations of APN predict coronary atherosclerotic heart disease and its prognosis. The anti-inflammatory and stable plaque effect of APN can treat coronary atherosclerotic heart disease. Now in recent years at home and abroad on the APN and coronary heart disease prediction, diagnosis and treatment of related literature are reviewed.